Combinatorial microfluidic droplet engineering for biomimetic material synthesis
نویسندگان
چکیده
منابع مشابه
Combinatorial microfluidic droplet engineering for biomimetic material synthesis
Although droplet-based systems are used in a wide range of technologies, opportunities for systematically customizing their interface chemistries remain relatively unexplored. This article describes a new microfluidic strategy for rapidly tailoring emulsion droplet compositions and properties. The approach uses a simple platform for screening arrays of droplet-based microfluidic devices and cou...
متن کاملA Droplet Microfluidic Platform for Automating Genetic Engineering.
We present a water-in-oil droplet microfluidic platform for transformation, culture and expression of recombinant proteins in multiple host organisms including bacteria, yeast and fungi. The platform consists of a hybrid digital microfluidic/channel-based droplet chip with integrated temperature control to allow complete automation and integration of plasmid addition, heat-shock transformation,...
متن کاملMicrofluidic platform for combinatorial synthesis in picolitre droplets.
This paper presents a droplet-based microfluidic platform for miniaturized combinatorial synthesis. As a proof of concept, a library of small molecules for early stage drug screening was produced. We present an efficient strategy for producing a 7 × 3 library of potential thrombin inhibitors that can be utilized for other combinatorial synthesis applications. Picolitre droplets containing the f...
متن کاملHelical Rosette Nanotubes as a Biomimetic Tissue Engineering Scaffold Material
With the rapid development of orthopedic implant technology, various bone implant surgeries and procedures (such as bone fractures, repairing defects, and hip and knee replacements) are routinely performed. Although these surgeries are usually successful operations for up to 15 years, implant failure due to loosening of the prostheses does occur for active or heavy patients. Other patients rece...
متن کاملInterfacial organic synthesis in a simple droplet-based microfluidic system.
A spherical liquid-liquid interface can be obtained by dispersing one liquid phase into another to form droplets, which will facilitate the two-phase reactions between the immiscible participating fluids. The phase transfer catalysts assembled at the droplet "wall" catalyze the reactions between the aqueous and organic phases. The study illustrates an interfacial synthetic approach which is ide...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Science Advances
سال: 2016
ISSN: 2375-2548
DOI: 10.1126/sciadv.1600567